Endocrine Abstracts

Introduction: Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes, combined together, under the name of MELAS syndrome, constitute one of the mitochondrial genetic diseases with dominant progressive neurodegenerative symptoms. Although nervous system involvement is often the first manifestation of the disease, during the course of the disorder, patient can develop a wide spectrum of endocrine disorders ranging from GH deficiency and hypoparathyroi...

Introduction: Pituitary apoplexy is a rare endocrine disorder which can occur due to haemorrhage into pituitary gland. It is often associated with the presence of pituitary adenoma, uncommonly being the first clinical manifestation of an underlying tumour. It can cause hypopituitarism and diabetes insipidus. Pituitary adenomas are classified by their secretion properties as functional and clinically non-functioning, the latter, however, can exhibit positive immunostaining for ...

Introduction: Acromegaly is a rare endocrinopathy which shows characteristic phenotypic and metabolic features. Primarily patients in their forties or fifties suffer from this disorder but the main problem is late diagnosis, especially in men, even 10 years after the first symptoms. We present an unusual clinical course of acromegaly with no phenotypic features to stress the need to perform complete evaluation of endocrine function in hypogonadal patients.<p class="abstext...